The use of desmopressin (DDAVP) for nocturia in women with multiple sclerosis.
نویسندگان
چکیده
Sixteen women with multiple sclerosis who complained of nocturia completed a double-blind cross-over trial of Desmopressin (DDAVP) and placebo. Nocturia was reduced from a mean of 2.55 voids to 2.01 with placebo and to 1.28 with Desmopressin (p less than 0.01, for the difference between placebo and Desmopressin). Side effects were minor, and equally distributed between treatment and placebo.
منابع مشابه
اثر دسموپرسین خوراکی بر شب ادراری ناشی از بزرگی خوش خیم پروستات: نتایج کوتاه مدت و بلند مدت
Received: 6 April, 2010 Accepted: 14 April, 2010 Abstract Background & Aims : Nocturia is a common symptom of benign prostatic hyperplasia (BPH). It may be treated with a blockers and 5 a reductase inhibitors, but in some patients, nocturia remains. In this study we assessed the short term and long term effects of oral desmopressin in patients with nocturia due to BPH. Materials & Met...
متن کاملInfluence of Type of Nocturia and Lower Urinary Tract Symptoms on Therapeutic Outcome in Women Treated With Desmopressin
PURPOSE To investigate the type of nocturia and concomitant voiding dysfunction (VD) and the effect of desmopressin treatment on nocturia in women. MATERIALS AND METHODS We reviewed 84 women who experienced more than 2 nocturia episodes as recorded on a pretreatment frequency volume chart and who were treated with desmopressin. All patients underwent history taking, physical examination, urin...
متن کاملDesmopressin in the treatment of daytime urinary frequency in patients with multiple sclerosis.
Twenty two patients with multiple sclerosis, complaining of frequency of day time micturition, completed a double blind crossover trial of desmopressin (DDAVP nasal spray) versus placebo. There was a significant decrease in micturition frequency in the 6 hour post-treatment period from 3.1 voids after placebo to 2.4 voids and a significant reduction in urinary volume after desmopressin. Eighty ...
متن کاملDesmopressin for the treatment of adult nocturia
10.2217/14750708.5.5.667 © 2 Nocturia is a bothersome and prevalent condition. It affects men and women equally, with an increasing incidence with age. It has multifactorial etiology and therefore treatment is based on an accurate history and examination with an assessment that should include frequency/volume charts and quality-of-life questionnaires. Treatment is primarily aimed at the etiolog...
متن کاملEffects of desmopressin for the treatment of nocturnal polyuria in elderly women: impact on related sleep quality.
INTRODUCTION We investigated the efficacy, safety, and impact of desmopressin on quality of sleep in treating nocturnal polyuria in elderly women. METHODS We recruited 60 women over 60 years old with lower urinary tract symptoms (LUTS), including nocturia, and with nocturnal polyuria. Nocturnal polyuria was defined as nighttime urine production exceeding 33% of the 24-hour total urine volume ...
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 46 9 شماره
صفحات -
تاریخ انتشار 1983